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SARS-CoV-IN-6

SKU: orb2664913

Description

SARS-CoV-IN-6 (Compound 17) acts as an inhibitor of SARS-CoV-1 and SARS-CoV-2 RdRp, demonstrating an IC50 value of 7.8 μM against SARS-CoV-2 RdRp. This compound reduces the cytopathic effects of single-round infectious particles (SRIP) infected with SARS-CoV-1 and SARS-CoV-2 replicons and inhibits the expression of SARS-CoVN proteins. The EC50 values for SRIP based on SARS-CoV-1 and SARS-CoV-2 replicons are 0.12 µM and 1.47 µM, respectively.

Research Area

,Microbiology/Virology

Images & Validation

Key Properties

CAS Number2244671-47-2
MW447.53
Purity98.00%
FormulaC25H29N5O3
SMILESC(N1C[C@@]2(C=3N(C[C@@](C2)(C1)[H])C(=O)C(NCC=4C(=O)N(C)C(=O)N(C)C4)=CC3)[H])C5=CC=CC=C5

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information