SB-1295

SKU: orb2278064

Description

SB-1295, an orally active CDK9/T1 inhibitor with an IC50 of 0.17 μM, exhibits antiproliferative effects on HCT 116 and MIA PaCa-2 cells. It promotes cell death in MIA PaCa-2 by elevating intracellular ROS levels, diminishing mitochondrial membrane potential, and triggering apoptosis. This compound holds potential for cancer research [1].

Research Area

,Metabolism|||NF-κB|||Immunology/Inflammation

Key Properties

• MW: 443.88
• Purity: 98.00%
• Formula: C₂₃H₂₂ClNO₆

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only