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SEMA4B Protein, Human, Recombinant (His)

SKU: orb1960991

Description

The class 4 semaphorins are integral membrane proteins that are widely expressed throughout the nervous system. SEMA4B is a single-pass type I membrane protein and contains one Ig-like C2-type (immunoglobulin-like) domain, one PSI domain and one Sema domain. Human SEMA4B is expressed in neurons. SEMA4B inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. SEMA4B negatively regulates basophil-mediated Th2 and humoral memory responses.

Research Area

,Recombinant-Protein

Images & Validation

Key Properties

Expression SystemHEK293 Cells
Biological OriginHuman
Biological ActivityThe class 4 semaphorins are integral membrane proteins that are widely expressed throughout the nervous system. SEMA4B is a single-pass type I membrane protein and contains one Ig-like C2-type (immunoglobulin-like) domain, one PSI domain and one Sema domain. Human SEMA4B is expressed in neurons. SEMA4B inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. SEMA4B negatively regulates basophil-mediated Th2 and humoral memory responses.
TagC-6xHis
Expression RegionLeu39-Glu712
MW86 KDa (reducing condition)
Purity98.00%
Protein SequenceLeu39-Glu712

Storage & Handling

Storage-20°C
Expiration Date6 months from date of receipt.
DisclaimerFor research use only

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  • Human SEMA4B Protein, His Tag [orb1743358]

    The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

    The protein has a predicted molecular mass of 75.4 kDa after removal of the signal peptide. The apparent molecular mass of SEMA4B-His is approximately 70-100 kDa due to glycosylation.

    Mammalian

    100 μg, 10 μg, 50 μg
  • SEMA4B Protein, Human, Recombinant (hFc & His) [orb1960992]

    98.00%

    114 KDa (reducing condition)

    1 mg, 500 μg, 50 μg, 10 μg
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SEMA4B Protein, Human, Recombinant (His) (orb1960991)

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10 μg
$ 290.00
50 μg
$ 650.00
500 μg
$ 2,170.00
1 mg
$ 3,070.00
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