SGK1 Antibody

SKU: orb2637475

Description

SGK1 (Serine/threonine-protein kinase 1) is a member of a serine/threonine subfamily of kinases. This kinase is involved in a wide variety of cellular functions including cell growth, survival and migration as well as a wide variety of cellular processes including transcription (Foxo3A, b-catenin, NF-kB, and p53), stress response and apoptosis. SGK1 also participates in neuronal function. Expression of SGK1 is stimulated by amphetamine, LSD and neuronal injury, it stimulates dendrite growth, is important in long term memory, fear-conditioning/spatial/novel object recognition learning and is likely involved in the pathophysiology of Alzheimer's disease.

Images & Validation

• Tested Applications: WB
• Dilution Range: Western blot: 1-3ug/ml
• Reactivity: Human
• Application Notes:
  Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Immunogen: A recombinant protein fragment from the C-terminal region of human SGK1 was used as the immunogen for this antibody.
• Purity: Protein A affinity chromatography
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 1X PBS, pH 7.4
• Expiration Date: 12 months from date of receipt.
• Hazard Information: This SGK1 antibody is available for research use only.
• Disclaimer: For research use only

Quick Database Links

NCBI Gene ID

6446