SH3RF1 (C2) Antibody, Rabbit Polyclonal

SKU: orb131734

Description

Rabbit polyclonal to SH3RF1. E3 ubiquitin-protein ligase SH3RF1 belongs to the SH3RF family. SH3RF1 acts as a scaffold protein, contributes to Rac-induced signal transduction such as JNKs (MAPK8 and MAPK9) activation and induces apoptosis. Within a signaling complex, it probably recruits protein kinases such as MAP3K10 or MAP3K11 which are in turn activated leading to the sequential activation of MAP2K4, MAP2K7 and JNKs (MAPK8 and MAPK9). SH3RF1 may be involved in targeting of HIV-1 GAG and GAG-POL polyproteins to the plasma membrane.

Research Area

Epigenetics,Product Categories/Products/Antibodies,Infectious Diseases,Product Categories/Products/Antibodies/Primary Antibodies

Images & Validation

• Tested Applications: WB
• Dilution Range: WB:1:1000-1:3000
• Reactivity: Human, Mouse
• Application Notes:
  < strong>WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.; < br>< strong>Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human SH3RF1.

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: C-terminal region of human SH3RF1
• Molecular Weight: 93
• Purity: Affinity purification
• Conjugation: Unconjugated

Storage & Handling

• Storage: -20°C
• Buffer/Preservatives: 0.01% NaN3
• Concentration: 100 μg/ml BSA
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti E3 ubiquitin-protein ligase SH3RF1 antibody, anti Plenty of SH3s antibody, anti Protein POSH antibody, anti RING finger protein 142 antibody, anti SH3 domain-containing RING finger protein 1 antibody, anti SH3 multiple domains protein 2 antibody, anti KIAA1494 antibody, anti POSH antibody, anti RNF142 antibody, anti SH3MD2 antibody

Quick Database Links

UniProt

Q7Z6J0