SHANK1 Antibody: APC

SKU: orb148619

Description

Mouse monoclonal to SHANK1 (APC). Shank proteins make up a family of scaffold proteins identified through their interaction with a variety of membrane and cytoplasmic proteins. Shank1 specifically might be relevant to human autism spectrum disorders, due to its differential role in specific cognitive processes, along with its importance for synapse structure and function in vivo..

Research Area

Product Categories/Products/Antibodies,Product Categories/Research Area,Product Categories/Products/Antibodies/Primary Antibodies,Epigenetics,Neuroscience | Cell Markers | Neuron Markers | Postsynaptic Markers | Cell Signaling | Scaffold Proteins

Images & Validation

• Tested Applications: ICC, IF, IHC
• Dilution Range: WB (1:1000), IHC (1:1000), ICC/IF (1:100)
• Reactivity: Human, Mouse, Rat
• Application Notes:
  1 µg/ml of SMC-329 was sufficient for detection of Shank1 in 10 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1
• Clone No.: N22/21 (Formerly sold as S22-21)
• Immunogen: Fusion protein amino acids 469-691 (SH3/PDZ domains) of rat Shank1
• Target: SHANK1
• Molecular Weight: 190-220 kDa
• Conjugation: APC

Storage & Handling

• Storage: Conjugated antibodies should be stored according to the product label
• Buffer/Preservatives: 95.64mM Phosphate, 2.48mM MES and 2mM EDTA
• Concentration: 1 mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

GKAP/SAPAP interacting protein antibody, OTTHUMP00000174437 antibody, SH3 and multiple ankyrin repeat domains 1 antibody, SH3 and multiple ankyrin repeat domains protein 1 antibody, SH3/ankyrin domain gene 1 antibody, SHAN1_HUMAN antibody, SHANK 1 antibody, Shank1 antibody, Shank1a antibody, Somatostatin receptor interacting protein antibody, Somatostatin receptor-interacting protein antibody, SPANK 1 antibody, SPANK1 antibody, SSTR interacting protein antibody, SSTR-interacting protein antibody, SSTRIP antibody, Synamon antibody

Quick Database Links

Gene Symbol

SHANK1

UniProt

Q9WV48

NCBI Gene ID

78957

RefSeq (Protein):NP_113939.2