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SIRT7 inhibitor 97491

SKU: orb1472995

Description

SIRT7 inhibitor 97491, a potent SIRT7 inhibitor with an IC50 of 325 nM, reduces deacetylase activity of SIRT7 in a dose-dependent manner. SIRT7 inhibitor 97491 prevents tumor progression by increasing p53 stability through acetylation at K373/382. SIRT7 inhibitor 97491 promotes apoptosis through caspase pathway..

Research Area

Product Categories/Products/Small Molecules

Images & Validation

Key Properties

CAS Number[1807758-81-1]
MW285.73
FormulaC15H12ClN3O
SMILESNC1=CC(NC2=NC=C(C3=CC=C(Cl)C=C3)O2)=CC=C1

Storage & Handling

Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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  • SIRT7 inhibitor 97491 [orb1303559]

    98%

    1807758-81-1

    285.73

    C15H12ClN3O

    100 mg, 1 mg, 50 mg, 5 mg, 10 mg, 25 mg, 1 ml x 10 mm (in DMSO)
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100 mg
$ 1,020.00
250 mg
$ 1,800.00