SKI V

SKU: orb692102

Description

SKI V is a noncompetitive and potent non-lipid sphingosine kinase (SPHK; SK) inhibitor with an IC50 of 2 μM for GST-hSK. SKI V potently inhibits PI3K with an IC50 of 6 μM for hPI3k. SKI V decreases formation of the mitogenic second messenger sphingosine-1-phosphate (S1P). SKI V induces apoptosis and has antitumor activity[1][2].

Research Area

Product Categories/Products/Small Molecules,Product Categories/Products/Small Molecules/Inhibitors

Key Properties

• CAS Number: [24418-86-8]
• MW: 254.23
• Formula: C₁₅H₁₀O₄
• SMILES: O=C1C2C(=CC=CC=2)O/C/1=C\C1C=C(O)C(O)=CC=1

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only