Sorafenib free base (BAY-43-9006)

SKU: orb341707

Description

Sorafenib(BAY 43-9006) is a potent inhibitor of Raf-1 with IC50 values of 6 nM, 22 nM and 90 nM for Raf-1, B-Raf, and VEGFR2 respectively, BAY 43-9006 suppresses both wild-type and V599E mutant BRAF activity in vitro.

Research Area

Product Categories/Products/Small Molecules

Key Properties

• CAS Number: [284461-73-0]
• MW: 464.82
• Formula: C₂₁H₁₆ClF₃N₄O₃
• SMILES: C(C(NC)=O)1=NC=CC(OC2=CC=C(NC(NC3=CC=C(Cl)C(C(F)(F)F)=C3)=O)C=C2)=C1

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only