STAT1 Antibody (C-term)

SKU: orb107084

Description

Rabbot polyclonal to STAT1. The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq].

Research Area

Product Categories/Products/Antibodies,Product Categories/Research Area,Neuroscience,Epigenetics,Infectious Diseases,Host-virus interaction;Jak-STAT signaling KEGG;JAK-STAT signaling;Interleukin signaling;Interferon-gamma signaling;Inflammation mediated by chemokine and cytokine signaling;Chemokine signaling;Immune system process;Toll-Like receptor signaling;Crown Antibodies;Antiviral defense;Signal Transduction;Neuroscience;Microbiology;Metabolism;Cardiovascular;Cancer;Primary Antibodies

Images & Validation

• Tested Applications: FC, IF, IHC-P, WB
• Dilution Range: WB: 1:1000
• Reactivity: Human

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Clone No.: RB41406
• Immunogen: Synthetic Peptide
• Target: STAT1
• Molecular Weight: 87335
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
• Form/Appearance: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti STAT1 antibody, anti Signal transducer and activator of transcription 1-alpha/beta antibody, anti Transcription factor ISGF-3 components p91/p84 antibody

Quick Database Links

Gene Symbol

STAT1

UniProt

P42224

RefSeq (Protein):NP_644671.1, NP_009330.1