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STAT3-IN-34

SKU: orb2665259

Description

STAT3-IN-34 (Compound 15E) acts as a STAT3 inhibitor, blocking both the nuclear translocation and the transcriptional regulator activity of STAT3. It effectively inhibits HaCaT cell proliferation with an IC50 value of 0.008 μM. Additionally, STAT3-IN-34 reduces IL-17A expression and mitigates Imiquimod-induced psoriasis in mouse models.

Research Area

,JAK/STAT signaling|||Stem Cells

Images & Validation

Key Properties

MW368.41
Purity98.00%
FormulaC19H16N2O4S

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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STAT3-IN-34 (orb2665259)

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