STAT3/HDAC-IN-2

SKU: orb2665286

Description

STAT3/HDAC-IN-2 (compound 18), a dual inhibitor of STAT3 and HDAC, promotes autophagy and apoptosis. This compound features an amphiphilic hydroxamic acid hybrid structure, derived from the natural product isopropanol lactone (IAL), and functions as a nanoscale anticancer agent. It has the ability to self-assemble into nanoparticles in aqueous environments, leading to enhanced tumor tissue accumulation, increased cellular uptake, and improved anticancer efficacy compared to its free state.

Research Area

,Stem Cells|||Chromatin/Epigenetic|||JAK/STAT signaling|||DNA Damage/DNA Repair

Key Properties

• MW: 508.56
• Purity: 98.00%
• Formula: C₂₈H₃₂N₂O₇

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only