SUMO2 Antibody (C-term)

SKU: orb134982

Description

Rabbit polyclonal to SUMO2. Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins.

Research Area

Product Categories/Products/Antibodies,Product Categories/Research Area,Product Categories/Products/Antibodies/Primary Antibodies,Epigenetics,Crown Antibodies;Primary Antibodies;Cell Biology

Images & Validation

• Tested Applications: IF, WB
• Dilution Range: WB: 1:1000
• Reactivity: Human, Rat
• Predicted Reactivity: Hamster, Mouse, Porcine

Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG2b
• Clone No.: 973CT8.1.1
• Immunogen: Recombinant Protein
• Target: SUMO2
• Molecular Weight: 10871
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
• Form/Appearance: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti SUMO2 antibody, anti SMT3A antibody, anti SMT3H2 antibody, anti Small ubiquitin-related modifier 2 antibody, anti Small ubiquitin-related modifier 2 antibody, anti HSMT3 antibody, anti Small ubiquitin-related modifier 2 antibody, anti SMT3 homolog 2 antibody, anti Small ubiquitin-related modifier 2 antibody, anti SUMO-3 antibody, anti Small ubiquitin-related modifier 2 antibody, anti Sentrin-2 antibody, anti Small ubiquitin-related modifier 2 antibody, anti Ubiquitin-like protein SMT3A antibody

Quick Database Links

Gene Symbol

SUMO2

UniProt

P61956

RefSeq (Protein):NP_008868.3, NP_001005849.1