SUZ12 Antibody (C-term)

SKU: orb106948

Description

Rabbit polyclonal to SUZ12. Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates Lys-9 (H3K9me) and Lys-27 (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.

Research Area

Product Categories/Products/Antibodies,Product Categories/Research Area,Cancer,Product Categories/Products/Antibodies/Primary Antibodies,Epigenetics,Primary Antibodies

Images & Validation

• Tested Applications: WB
• Dilution Range: WB: 1:1000
• Reactivity: Human, Mouse

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Clone No.: RB42757
• Immunogen: Synthetic Peptide
• Target: SUZ12
• Molecular Weight: 83055
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
• Form/Appearance: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti SUZ12 antibody, anti CHET9 antibody, anti JJAZ1 antibody, anti KIAA0160 antibody, anti Polycomb protein SUZ12 antibody, anti Polycomb protein SUZ12 antibody, anti Chromatin precipitated E2F target 9 protein antibody, anti Polycomb protein SUZ12 antibody, anti Joined to JAZF1 protein antibody, anti Polycomb protein SUZ12 antibody, anti Suppressor of zeste 12 protein homolog antibody

SUZ12 Antibody (C-term) western blot analysis in Ramos cell line lysates (35 ug/lane). This demonstrates the SUZ12 antibody detected the SUZ12 protein (arrow).

Anti-SUZ12 Antibody (C-term) at 1:2000 dilution + F9 whole cell lysate.Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size: 83 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.

Quick Database Links

Gene Symbol

SUZ12

UniProt

Q15022

RefSeq (Protein):NP_056170.2