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SW063058

SKU: orb2695674

Description

SW063058 is an autophagy inducer that specifically disrupts the interaction between Beclin 1 and Bcl-2 without affecting the interactions of Bcl-2 with pro-apoptotic members (such as Bax and BIM). By inhibiting the negative regulation of Beclin 1 (key to autophagy initiation) by Bcl-2, SW063058 enhances autophagic activity without inducing cytotoxicity, apoptosis, or other forms of cell death in vitro.

Research Area

,Others

Images & Validation

Key Properties

CAS Number533876-30-1
MW565.17
FormulaC22H15BrFIN2O2
SMILESO=C1NC2=CC=C(Br)C=C2C(C3=CC=C(F)C=C3)N(C(=O)C=4C=CC=CC4I)C1

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information