SZM-1209

SKU: orb1944809

Description

SZM-1209 is a potent and specific RIPK1 inhibitor with oral activity, displaying a dissociation constant (Kd) of 85 nM. It demonstrates substantial anti-necroptotic efficacy with an EC50 of 22.4 ± 8.1 nM and possesses therapeutic effects against systemic inflammatory response syndrome (SIRS) and acute lung injury (ALI) [1].

Research Area

,Apoptosis|||NF-κB

Key Properties

• CAS Number: 2919801-86-6
• MW: 696.71
• Purity: 98.00%
• Formula: C₃₁H₂₉F₅N₄O₅S₂

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only