Taltobulin hydrochloride

SKU: orb1982182

Description

Taltobulin hydrochloride (HTI-286 hydrochloride), a synthetic analogue of the tripeptide hemiasterlin, effectively bypasses P-glycoprotein-mediated resistance both in vitro and in vivo as a robust antimicrotubule agent. It prevents the polymerization of purified tubulin, destabilizes cellular microtubule structures, and triggers both mitotic arrest and apoptosis [1].

Research Area

,Antibody-drug Conjugate/ADC Related

Key Properties

• MW: 510.11
• Purity: 98.00%
• Formula: C₂₇H₄₄ClN₃O₄

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only