TARP Gamma2/4/8 (Stargazin) Antibody: HRP

SKU: orb150203

Description

Mouse monoclonal to TARP Gamma2 (HRP). Stargazin belongs to a group called voltage gated calcium channels (VGCCs) which are present in most excitable cells. Stargazin is thought to stabilize the calcium channel in an inactivated (closed) state. There are five high voltage activated calcium channel types (L, N, P, Q, and R) and one low voltage activated channel type (T). Each of these channels exists as a heteromultimer of a1, b, a2/ d and g subunits with the voltage activated calcium channel function carried by the a subunits. VGCCs exert spatial and temporal control over cellular calcium concentrations and serve to modulate neurotransmitter release, hormone secretion, muscle contraction, electrical activity, cell metabolism and proliferation, gene expression, and neuronal survival..

Research Area

Product Categories/Products/Antibodies,Product Categories/Research Area,Product Categories/Products/Antibodies/Primary Antibodies,Epigenetics,Neuroscience | Ion Channels | Calcium Channels | Voltage-Gated Calcium Channels | Cell Markers | Neuron Markers | Postsynaptic Markers

Images & Validation

• Tested Applications: ELISA, IHC, WB
• Dilution Range: WB (1:1000), ICC/IF (1:100)
• Reactivity: Human, Mouse, Rat
• Application Notes:
  1 µg/ml of SMC-422 was sufficient for detection of TARP Gamma2/4/8 in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG2A
• Clone No.: N245/36 (Formerly sold as S245-36)
• Immunogen: Fusion protein amino acids 203-323 (Cytoplasmic C-terminus) of rat TARPGamma2
• Target: Stargazin
• Molecular Weight: 35-55kDa
• Conjugation: HRP

Storage & Handling

• Storage: Conjugated antibodies should be stored according to the product label
• Buffer/Preservatives: 73.64mM Carbonate, 54.55mM Ethanolamine, 45.45mM Cyanoborohydride, 18.18mM Sodium Hydroxide and 0.23mM Citrate in dH2O
• Concentration: 1 mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CACNG2 antibody, Calcium channel voltage dependent gamma subunit 2 antibody, CaV gamma 2 antibody, Ipr328 antibody, MGC123981 antibody, MGC138502 antibody, MGC138504 antibody, Voltage-dependent calcium channel gamma-2 subunit antibody, Neuronal voltage-gated calcium channel gamma-2 subunit antibody, Stargazin antibody, Stg antibody, Stargazer antibody, TARP antibody, TARP gamma-2 antibody, Transmembrane AMPAR regulatory protein gamma-2 antibody, AW060990 antibody, B230105C07Rik antibody, B930041E13Rik antibody, Wag antibody, Waggler antibody

Quick Database Links

Gene Symbol

Stargazin

UniProt

Q71RJ2

NCBI Gene ID

84347

RefSeq (Protein):NP_445803.1