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Teriflunomide (A-771726)
SKU: orb146201
Description
Research Area
Product Categories/Products/Small Molecules,Product Categories/Products/Small Molecules/Inhibitors
Images & Validation
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Key Properties
−| CAS Number | [163451-81-8] |
|---|---|
| MW | 270.21 |
| Formula | C12H9F3N2O2 |
| SMILES | C(NC1=CC=C(C(F)(F)F)C=C1)(=O)/C(/C#N)=C(\O)/C |
Storage & Handling
−| Storage | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
|---|---|
| Expiration Date | 12 months from date of receipt. |
| Hazard Information | Non-Toxic |
| Disclaimer | For research use only |
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Protocol Information
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Groh, Janos et al. Immune modulation attenuates infantile neuronal ceroid lipofuscinosis in mice before and after disease onset Brain Commun, 3, (2021)
Applications
In vivo
Reactivity
Mouse
Hörner, Michaela et al. CNS-associated T-lymphocytes in a mouse model of Hereditary Spastic Paraplegia type 11 (SPG11) are therapeutic targets for established immunomodulators Exp Neurol, 355, 114119 (2022)
Applications
In vivo
Reactivity
Mouse
Groh, Janos et al. Fingolimod and Teriflunomide Attenuate Neurodegeneration in Mouse Models of Neuronal Ceroid Lipofuscinosis Mol Ther, 25, 1889-1899 (2017)
Applications
In vivo
Reactivity
Mouse
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