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Testin Protein, Human, Recombinant (His)

SKU: orb1960963

Description

Testin belongs to the prickle/espinas/testin family. Testin contains three LIM zinc-binding domains and one PET domain, TES as a scaffold protein that may have a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. In addition, TES can also as a tumor suppressor, inhibits tumor cell growth, regulate the cell proliferation.TES interacts with many cytoskeletal proteins, such as Zyxin, Mena, Actin, Talin and VASP. The ability of TES to associate with alpha-actin, Zyxin and paxillin is dependent on the conformational state of the molecule.

Research Area

,Recombinant-Protein

Images & Validation

Key Properties

Expression SystemE. coli
Biological OriginHuman
Biological ActivityTestin belongs to the prickle/espinas/testin family. Testin contains three LIM zinc-binding domains and one PET domain, TES as a scaffold protein that may have a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. In addition, TES can also as a tumor suppressor, inhibits tumor cell growth, regulate the cell proliferation.TES interacts with many cytoskeletal proteins, such as Zyxin, Mena, Actin, Talin and VASP. The ability of TES to associate with alpha-actin, Zyxin and paxillin is dependent on the conformational state of the molecule.
TagC-6xHis
Expression RegionMet1-Ser421
MW50 KDa (reducing condition)
Purity98.00%
Protein SequenceMet1-Ser421

Storage & Handling

Storage-20°C
Expiration Date6 months from date of receipt.
DisclaimerFor research use only

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    100 μg, 50 μg
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UniProt Details

No UniProt data available

Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
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10 μg
$ 230.00
50 μg
$ 490.00
500 μg
$ 2,000.00
1 mg
$ 2,830.00
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