TIM3 / HAVCR2 / CD366 (Effector T-Cell Marker) Antibody

SKU: orb2320170

Description

TIM3 / HAVCR2 / CD366 (Effector T-Cell Marker) Antibody

Research Area

,Cardiovascular|Cytokine Signaling|Immunology

Images & Validation

• Tested Applications: ELISA, IHC
• Dilution Range: Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 min at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
• Reactivity: Human
• Application Notes:
  Positive Control: PC3, BT474, HepG2, HDLM-2 or Daudi cells. Tonsil, lymph node or spleen.

Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG2a
• Clone No.: TIM3/3113
• Immunogen: Recombinant fragment of human TIM3 protein (around aa 22-202) (exact sequence is proprietary)
• Target: HAVCR2
• Source/Expression System: HEK293 cells
• Molecular Weight: 60kDa
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: 200ug/ml of Ab produced in HEK293 cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% rAlbumin & 0.05% azide. Also available WITHOUT rAlbumin & azide at 1.0mg/ml.
• Concentration: Purified Ab with BSA and Azide at 200ug/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CD366; HAVR2; Hepatitis A virus cellular receptor 2 (HAVCR2); Kidney injury molecule 3 (KIM3); T-cell immunoglobulin and mucin domain-containing protein 3; T-cell immunoglobulin mucin receptor 3; T-cell membrane protein 3; TIM3; TIMD3

Quick Database Links

Gene Symbol

HAVCR2

UniProt

Q8TDQ0

NCBI Gene ID

84868