TLR3 (M) Antibody, Rabbit Polyclonal

SKU: orb131819

Description

Rabbit polyclonal to TLR3. Toll-like receptor 3 (TLR3) belongs to the Toll-like receptor family and is a key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Additionally, TLR3 acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.

Research Area

Product Categories/Products/Antibodies,Epigenetics,Immunology,Product Categories/Products/Antibodies/Primary Antibodies

Images & Validation

• Tested Applications: WB
• Dilution Range: WB:1:1000-1:3000
• Reactivity: Human
• Application Notes:
  < strong>WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.; < br>< strong>Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the middle region of human TLR3.

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: middle region of human TLR3
• Molecular Weight: 104
• Purity: Affinity purification
• Conjugation: Unconjugated

Storage & Handling

• Storage: -20°C
• Buffer/Preservatives: 0.01% NaN3
• Concentration: 100 μg/ml BSA
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti Toll-like receptor 3 antibody, anti CD283 antibody

Quick Database Links

UniProt

O15455