Top1/2-IN-1

SKU: orb2665308

Description

Compound 23, known as Top1/2-IN-1, is a dual inhibitor of Top1/2 that can be administered orally and exhibits antiproliferative effects. It induces apoptosis and cell cycle arrest in cancer cells by damaging DNA and elevating reactive oxygen species levels. Additionally, Top1/2-IN-1 demonstrates antitumor activity in vivo within xenograft models.

Research Area

,DNA Damage/DNA Repair

Key Properties

• MW: 347.41
• Purity: 98.00%
• Formula: C₂₁H₂₁N₃O₂

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only