TrpC7 Antibody: APC

SKU: orb148857

Description

Mouse monoclonal to TrpC7 (APC). Transient receptor potential cation channel, subfamily C, member 7, also known as TRPC7, is a non-selective cation channel that is directly activated by DAG. TrpC7 shows constitutive activity and susceptibility to negative regulation by extracellular Ca2+. Because of this, TrpC7 plays an important role in the Ca2+ signaling pathway. TrpC7 is also expressed abundantly in the heart, and combined with its ability to act as a Ca2+ channel, TrpC7 might contribute to the process of heart failure..

Research Area

Product Categories/Products/Antibodies,Product Categories/Research Area,Product Categories/Products/Antibodies/Primary Antibodies,Epigenetics,Neuroscience | Ion Channels | Transient Receptor Potential (TRP) Channels | Cell Signaling

Images & Validation

• Tested Applications: ICC, IF, IHC
• Dilution Range: WB (1:1000), IHC (1:1000), ICC/IF (1:100)
• Reactivity: Human, Mouse, Rat
• Application Notes:
  1 µg/ml of SMC-343 was sufficient for detection of TrpC7 in 10 µg of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1
• Clone No.: N64A/36 (Formerly sold as S64A-36)
• Immunogen: Synthetic peptide amino acids 845-862 of human TRPC7
• Target: TRPC7
• Molecular Weight: 100kDa
• Conjugation: APC

Storage & Handling

• Storage: Conjugated antibodies should be stored according to the product label
• Buffer/Preservatives: 95.64mM Phosphate, 2.48mM MES and 2mM EDTA
• Concentration: 1 mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

TRP7 antibody, KNP3 antibody, TRPM2 antibody, transient receptor potential cation channel subfamily C member 7 antibody

Quick Database Links

Gene Symbol

TRPC7

UniProt

Q9HCX4

NCBI Gene ID

57113

RefSeq (Protein):NP_065122.1