Tucidinostat

SKU: orb2647069

Description

Tucidinostat (Chidamide, HBI-8000, CS055) is a novel histone deacetylase (HDAC) inhibitor with IC50 of 95/160/67/733/78/432 nM for HDAC1/2/3/8/10/11, respectively; shows no activity against Class IIa HDAC4/4/7/9 and HDAC6; demonstrates significant and broad spectrum in vitro and in vivo antitumor activity, induces G1 arrest, ROS-dependent apoptosis and differentiation in human leukaemia cells.

Key Properties

• CAS Number: [1616493-44-7]
• MW: 390.410268068314
• Formula: C₂₂H₁₉FN₄O₂
• SMILES: FC1C=CC(=C(C=1)N)NC(C1C=CC(=CC=1)CNC(/C=C/C1C=NC=CC=1)=O)=O

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only