VGLUT2 Antibody: FITC

SKU: orb149743

Description

Mouse monoclonal to VGlut2 (FITC). The ATP-dependent, chloride-sensitive vesicular glutamate transporters (VGLUT) include BNPI (VGLUT1), VGLUT2 (DNPI) and VGLUT3. The brain expresses BNPI (brain specific Na+-dependent inorganic phosphate (Pi) cotransporter) and VGLUT2 in a complementary fashion. The telencephalic regions express BNPI, whereas the lower brainstem and diencephalic regions express VLGUT2. Rat pinealocytes express both BNPI and VGLUT2. The striatum, hippocampus, cerebral cortex and raphe nuclei express VGLUT3 in a small number of neurons. Pancreatic alpha and beta cells express BNPI and VGLUT2 in response to glucose concentrations. Human VGLUT3 shares a 72% sequence homology with VLGUT2 and BNPI..

Research Area

Product Categories/Products/Antibodies,Product Categories/Research Area,Neuroscience,Product Categories/Products/Antibodies/Primary Antibodies,Epigenetics,Neuroscience | Cell Markers | Neuron Markers | Presynaptic Markers | Pumps/Transporters | Neurotransmitter Transporters | Cell Signaling

Images & Validation

• Tested Applications: ICC, IF, IHC
• Dilution Range: WB (1:1000), ICC/IF (1:100)
• Reactivity: Human, Mouse, Rat
• Application Notes:
  1 µg/ml of SMC-395 was sufficient for detection of VGLut2 in 20 µg of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1
• Clone No.: N29/29 (Formerly sold as S29-29)
• Immunogen: Fusion protein amino acids 501-582 (cytoplasmic C-terminus) of rat VGlut2
• Target: VGLUT2
• Molecular Weight: 60kDa
• Conjugation: FITC

Storage & Handling

• Storage: Conjugated antibodies should be stored according to the product label
• Buffer/Preservatives: 640.91mM DMSO, 136.36mM Ethanolamine, 9.09mM Sodium Bicarbonate in 90.9% PBS
• Concentration: 1 mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Differentiation associated BNPI antibody, DNPI antibody, SLC17A6 antibody, Solute carrier family 17 member 6 antibody, Vesicular glutamate transporter 2 antibody, Differentiation associated Na dependent inorganic phosphate cotransporter antibody, Solute carrier family 17 (Sodium dependent inorganic phosphate cotransporter) member 6 antibody, Differentiation associated Na(+) dependent inorganic phosphate cotransporter antibody, Differentiation-associated Na(+)-dependent inorganic phosphate cotransporter antibody, Sodium dependent inorganic phosphate cotransporter antibody

Quick Database Links

Gene Symbol

VGLUT2

UniProt

Q9JI12

NCBI Gene ID

84487

RefSeq (Protein):NP_445879.1