Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

Y-27632 2HCL

SKU: orb154626

Description

Y-27632 2HCl is a selective ROCK1 (p160ROCK) inhibitor with Ki of 140 nM.

Research Area

Product Categories/Products/Small Molecules,Product Categories/Products/Small Molecules/Inhibitors

Images & Validation

Key Properties

CAS Number[129830-38-2]
MW320.26
FormulaC14H23Cl2N3O
SMILESC[C@H](C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.Cl.Cl

Storage & Handling

StorageCan be stored for 2 years at -20°C in powder form, 2 weeks at 4°C in DMSO, and 6 months at -80°C in DMSO.
Expiration Date12 months from date of receipt.
Hazard InformationNon-Toxic
DisclaimerFor research use only

Similar Products

  • Y-27632 dihydrochloride [orb1307611]

    97.96% (May vary between batches)

    129830-38-2

    320.26

    C14H21N3O·2HCl

    5 mg, 10 mg, 1 ml x 10 mM (in DMSO), 100 mg, 1g, 25 mg, 50 mg
  • Y 27632 [orb1713678]

    ≥98% (HPLC)

    146986-50-7

    320.3

    C14H23Cl2N3O

    5 mg
  • Y 27632 [orb1713679]

    ≥98% (HPLC)

    146986-50-7

    320.3

    C14H23Cl2N3O

    1 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Protocol Information

Filter by Applications

Filter by Species

Barbora Schwarzova, Tim Studemann, Muhammed Sonmez, Judith Rossinger, Bangfen Pan, Thomas Eschenhagen, Justus Stenzig, J. Simon Wiegert, Torsten Christ & Florian Weinberger Modulating cardiac physiology in engineered heart tissue with the bidirectional optogenetic tool BiPOLES Pflugers Arch., (2023)

Applications

Cell Culture

Reactivity

Human

Karl T Wagner 1, Rick X Z Lu 1, Shira Landau 1, Sarah A Shawky 2, Yimu Zhao 1, David F Bodenstein 1, Luis Felipe Jiménez Vargas 1, Richard Jiang 3, Sargol Okhovatian 1, Ying Wang 1, Chuan Liu 1, Daniel Vosoughi 4, Dakota Gustafson 4, Jason E Fish 5, Carolyn L Cummins 6, Milica Radisic 1 Endothelial extracellular vesicles enhance vascular self-assembly in engineered human cardiac tissues Biofabrication, (2024)

J Raabe, I Wittig, P Laurette, K Stathopoulou, T Brand Physioxia rewires mitochondrial complex composition to protect stem cell viability Redox Biology, (2024)

Mireia Nàger 1, Kenneth B Larsen 2 3, Zambarlal Bhujabal 2, Trine B Kalstad 2, Judith Rössinger 4, Truls Myrmel 1 2, Florian Weinberger 4 5, Asa B Birgisdottir Mitophagy is induced in human engineered heart tissue after simulated ischemia and reperfusion J Cell Sci ., (2025)

Available Sizes

Select a size below

1 ml x 10 mm (in DMSO)
$ 390.00
100 mg
$ 750.00
250 mg
$ 1,280.00
1 g
$ 2,450.00
DispatchUsually dispatched within 5-10 working days
Bulk Enquiry