ZX782

SKU: orb2665328

Description

ZX782 acts as a GPX4 protein degrader and an inducer of ferroptosis (Ferroptosis), targeting GPX4 for destruction via both the ubiquitin-proteasome system and the autophagy-lysosome pathway. Following the degradation of GPX4 induced by ZX782, there is a significant increase in the accumulation of lipid reactive oxygen species (ROS) in HT1080 cells.

Research Area

,Apoptosis|||Metabolism

Key Properties

• MW: 750.28
• Purity: 98.00%
• Formula: C₃₉H₄₈ClN₅O₈

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only