ZZM-1220

SKU: orb2277695

Description

ZZM-1220, a covalent inhibitor of histone lysine methyltransferase G9a/GLP, exhibits IC50 values of 458 nM for G9a and 924 nM for GLP. It effectively inhibits H3K9me2 in cells, induces apoptosis in triple-negative breast cancer (TNBC) cells, and arrests the cell cycle at the G2/M phase [1].

Research Area

,Chromatin/Epigenetic

Key Properties

• MW: 447.53
• Purity: 98.00%
• Formula: C₂₅H₂₉N₅O₃

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only