AREG Protein, Human, Recombinant

SKU: orb1961448

Description

Amphiregulin (AREG) is a single-pass membrane protein with 252 amino acids. AREG belongs to the amphiregulin family, which contains 1 EGF-like domain. AREG is expressed in a variety of tissues including ovary, placenta, lung, kidney, stomach, colon, and breast. It is related to Epidermal Growth Factor (EGF) and Transforming Growth Factor Alpha (TGF-alpha). As an EGF-related growth factor, AREG interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. AREG may also play a protective role in Bleomycin-Induced Pneumopathy.

Research Area

,Recombinant-Protein

Images & Validation

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Application Notes	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.

Key Properties

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Expression System	E. coli
Biological Origin	Human
Biological Activity	Amphiregulin (AREG) is a single-pass membrane protein with 252 amino acids. AREG belongs to the amphiregulin family, which contains 1 EGF-like domain. AREG is expressed in a variety of tissues including ovary, placenta, lung, kidney, stomach, colon, and breast. It is related to Epidermal Growth Factor (EGF) and Transforming Growth Factor Alpha (TGF-alpha). As an EGF-related growth factor, AREG interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. AREG may also play a protective role in Bleomycin-Induced Pneumopathy.
Tag	Tag Free
Expression Region	Ser101-Lys198
MW	16 KDa (reducing condition)
Purity	98.00%
Protein Sequence	Ser101-Lys198

Storage & Handling

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Storage	-20°C
Expiration Date	6 months from date of receipt.
Disclaimer	For research use only

Human AREG Protein, hFc Tag [orb1290823]

Purity:	The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
MW:	The protein has a predicted molecular mass of 44.9 kDa after removal of the signal peptide. The apparent molecular mass of AREG-hFc is approximately 53-70 kDa due to glycosylation.
Source:	Mammalian

Sizes Available: 100 μg, 10 μg, 50 μg

Item 1 of 1
AREG (Human) Recombinant Protein (P01) [orb2290291]
Applications:
AP, Array, ELISA, WB
Sizes Available: 10 μg
Human AREG protein [orb391254]
Applications:
ELISA, MS, SDS-PAGE, WB
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Source:
E. coli
Sizes Available: 500 μg, 50 μg, 10 μg
Recombinant Human EGF [orb1921839]
Purity:
≥95%
MW:
6.2kDa
Source:
CHO Cell
Sizes Available: 50 mg, 1 mg, 10 mg

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Quick Database Links

UniProt

P15514

UniProt Details

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No UniProt data available

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