ENaC beta Antibody

SKU: orb67568

Description

Rabbit Anti-Rat ENaC beta Polyclonal

Research Area

Product Categories/Products/Antibodies,Product Categories/Products/Small Molecules,Product Categories/Research Area,Product Categories/Products/Antibodies/Primary Antibodies,Epigenetics,Neuroscience | Neurotransmission | Ion Channels | Sodium Channels | Epithelial Sodium Channels (ENaC)

Images & Validation

• Tested Applications: ICC, IF, IHC, IP, WB
• Dilution Range: WB (1:1000), IHC-P (1:100)
• Reactivity: Frog, Hamster, Human, Mouse, Rat
• Application Notes:
  1 µg/ml of SPC-404 was sufficient for detection of beta-ENaC in 20 µg of rat kidney tissue lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Produced against the C-terminal tail (amino acids 617-638) of rat beta ENaC (antibody designation 3755-2)
• Target: ENaC
• Molecular Weight: 87kDa
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: PBS, 50% glycerol, 0.09% sodium azide *Storage buffer changes when conjugated
• Concentration: 1 mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

SCNN1B Antibody, Amiloride sensitive sodium channel subunit beta Antibody, Amiloride-sensitive sodium channel beta-subunit Antibody, Beta ENaC Antibody, Beta NaCH Antibody, ENaC beta Antibody, ENaCB Antibody, Epithelial Na(+) channel subunit beta Antibody, Epithelial Na+ channel beta subunit Antibody, Epithelial Na+ channel subunit beta Antibody, Epithelial sodium channel beta 2 subunit Antibody, Epithelial sodium channel beta 3 subunit Antibody, Nonvoltage gated sodium channel 1 beta subunit Antibody, Nonvoltage gated sodium channel 1 subunit beta Antibody, Nonvoltage-gated sodium channel 1 beta subunit Antibody, SCNEB Antibody, SCNN 1B Antibody, Sodium channel nonvoltage gated 1 beta (Liddle syndrome) Antibody, Sodium channel nonvoltage gated 1 beta Antibody

Quick Database Links

Gene Symbol

ENaC

UniProt

P37090

NCBI Gene ID

24767

RefSeq (Protein):NP_036780

Ye Gao 1, Fei Cao 2, Xinyi Tian 1, Qianping Zhang 3, Congcong Xu 1, Bowen Ji 1, Ye-An Zhang 1, Linan Du 1, Jun Han 1, Li Li 1, Siyu Zhou 1, Yuqiang Gong 1, Binyu Ying 1, Fang Gao-Smith 4, Shengwei Jin Inhibition the ubiquitination of ENaC and Na,K-ATPase with erythropoietin promotes alveolar fluid clearance in sepsis-induced acute respiratory distress syndrome Biomed Pharmacother, 174, 116447 (2024)

PubMed: 38518606

Applications

WB

Reactivity

Rat

Han, Jun et al. Maresin Conjugates in Tissue Regeneration 1 improves alveolar fluid clearance by up-regulating alveolar ENaC, Na, K-ATPase in lipopolysaccharide-induced acute lung injury J. Cell. Mol. Med., 24, 4736-4747 (2020)

PubMed: 32160403