PKM2-IN-6

SKU: orb2565467

Description

PKM2-IN-6 (compound 7d) is a potent PKM2 inhibitor that can be administered orally and demonstrates an IC 50 value of 23 nM. It triggers apoptosis and causes cell cycle arrest in the G2 phase, while also reducing the mRNA levels of both PKM1 and PKM2. Additionally, PKM2-IN-6 exhibits anticancer properties and shows promise for research in triple-negative breast cancer [1].

Key Properties

• CAS Number: 771467-00-6
• MW: 322.38
• Purity: 98.00%
• Formula: C₁₇H₁₄N₄OS
• SMILES: N(C1=NC(C=2N3C(=NC2)C=CC=C3)=CS1)C4=C(OC)C=CC=C4

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

148613955