PKM2-IN-6

SKU: orb2647418

Description

PKM2-IN-6 (compound 7d) is a potent and orally active PKM2 inhibitor with an IC50 value of 23 nM. PKM2-IN-6 induces apoptosis and cell cycle arrest at G2 phase. PKM2-IN-6 reduces the level of PKM1 and PKM2 at the mRNA level. PKM2-IN-6 shows anticancer activity and has the potential for the research of triple-negative breast cancer.

Key Properties

• CAS Number: [771467-00-6]
• MW: 322.38
• Formula: C₁₇H₁₄N₄OS
• SMILES: COC1=CC=CC=C1NC2=NC(C3=CN=C4C=CC=CN43)=CS2

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only