Rat IL-7 protein

SKU: orb107751

Description

Interleukin-7 (IL-7) is encoded by the IL7 gene and secreted by stromal cells in the red marrow and thymus. It binds to the IL-7receptor, a heterodimer consisting of IL-7 receptor alpha and IL-2 receptor gamma chain. IL-7 stimulates the differentiation ofhematopoietic stem cells into lymphoid progenitor cells and also stimulates proliferation of B cells, T cells and NK cells.Furthermore, IL-7 as an immunotherapy agent has been examined in many human clinical trials for various malignancies andduring HIV infection. Rat IL-7 contains 129 amino acid residues and has three disulfide bonds. In addition, it has approximately57 % and 88 % amino acid sequence identity with human and murine IL-7.

Images & Validation

• Tested Applications: HPLC, SDS-PAGE

Key Properties

• Biological Origin: E.coli
• Target: IL-7
• Conjugation: Unconjugated
• MW: 14. 9 kDa
• Purity: > 95 % by SDS-PAGE and HPLC analyses
• Protein Sequence: DCHIKDKDGK AFGSVLMISI NQLDKMTGTD SDCPNNEPNF FKKHLCDDTKEAAFLNRAAR KLRQFLKMNI SEEFNDHLLR VSDGTQTLVN CTSKEEKTIKEQKKNDPCFL KRLLREIKTC WNKILKGSI

Storage & Handling

• Storage: Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
• Buffer/Preservatives: Lyophilized from a 0.2 m filtered concentrated solution in PBS, pH 7.4.
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Rat Interleukin-7 protein

SDS-PAGE analysis of Rat IL-7 protein

Quick Database Links

Gene Symbol

IL-7